Question
Was Enosh the first person to worship G-d?
Answer
Adam and Eve had personal contacts with G-d and certainly worshipped Him. What happened in the time of Adam’s grandson Enosh is that people began to treat created things (angels, heavenly bodies, etc.) as intermediaries between them and G-d; that’s what the Torah is referring to when it says "Then [men] began to call [other things] by the Name of G-d"